CHEM 299 Organic Chemistry 2*
Continuation of CHEM 298, including synthesis, qualitative organic analysis and spectroscopic methods.
CHEM 299Organic Chemistry 2*
Please note: This is not a course syllabus. A course syllabus is unique to a particular section of a course by instructor. This curriculum guide provides general information about a course.
I. General Information
II. Course Specification
Credit Hours Narrative
5 Credits
Prerequisite Narrative
CHEM 298
Corequisite Narrative
CHEM 299L
III. Catalog Course Description
Continuation of CHEM 298, including synthesis, qualitative organic analysis and spectroscopic methods.
IV. Student Learning Outcomes
Upon completion of this course, a student will be able to:
- Arenes: describe kekule form, stability, orbital hybridization, molecular orbitals and resonance picture of benzene; draw and name using common and IUPAC nomenclature derivatives of benzene; describe the physical properties of arenes; describe typical reactions involving arenes; use Huckel’s rule to predict aromaticity in arenes; describe the mechanistic principles of electrophilic aromatic substitution with typical reactions; describe and predict substitution effects in electrophilic aromatic substitution. Describe mechanisms and substitution patterns of nucleophilic substitution and birch reduction.
- Spectroscopy: describe the principles of electromagnetic radiation and quantized energy states; predict and interpret 1H and 13C spectra, describe and interpret fundamental infrared, UV vis, and mass spectroscopies.
- Aldehydes and ketones: describe the nomenclature, structure, bonding, and physical properties of aldehydes and ketones; describe the various reactions involving aldehydes and ketones including cyanohydrin formation and imine chemistry; describe the spectroscopic analysis of aldehydes and ketones.
- Enols and enolates: describe aldol condensations; describe enolization and stabilization issues; describe various reactions with emphasis on mechanisms involving ketones and aldehydes, describe conjugation effects as it pertains to ketones and aldehydes
- Alcohols and sulfur analogs: describe the sources, preparation and reactions of various types of alcohols; describe oxidation, ether and ester reactions and synthesis from alcohols and thiols; describe biological oxidation of various alcohols and thiols; describe the spectroscopic characteristics of alcohols and thiols.
- Ethers, epoxides, and sulfides: describe the nomenclature, structure, bonding, and physical properties; describe the preparation and reactions involving ethers, epoxides, and sulfides; describe the spectroscopic characteristics of ethers, epoxides, and sulfides.
- Carboxylic acids and derivatives: describe nomenclature, structure, bonding, and physical properties of carboxylic acids and their salts; describe the sources, synthesis, and reactions, including mechanisms; describe various reactions including esterification and lactone formation; describe the spectroscopic analysis of carboxylic acids
- Ester enolates: describe various reactions involving enolates including claisen condensations, acylations, ketone synthesis, Michael additions, and the use of LDA
- Amines: describe the nomenclature, structure, bonding, basicity, and physical properties of amines, describe various reactions for the preparation and use of a variety of amines, describe the spectroscopic analysis of amines.
- Organometallic compounds: demonstrate nomenclature master; describe carbon-metal bonds including the preparation of various organometallic reagents to form alcohols; describe the use and reactivity of organocopper and organozinc reagents; describe carbenes and carbenoids; describe various catalytic reactions using organometallic reagents
V. Topical Outline (Course Content)
VI. Delivery Methodologies