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Molecular, Cell, and Developmental Biology B.S.

Information and Policies

Introduction

The molecular, cell and developmental (MCD) biology major is designed to prepare students for rigorous graduate programs in biomedical research, medical and other healthcare professional programs, for careers in the biotechnology industry. This major is more structured than the general biology major and requires that students pay careful attention to the prerequisites required for upper-division biology courses. With proper advance planning, a student with virtually any degree can prepare a competitive application for medical school or healthcare professional school. Check our Health Careers webpage for more information on how you can academically prepare for a career in healthcare. Additional information is available at the UC Santa Cruz Career Center.

Program Learning Outcomes

Students who successfully complete the MCD major will be able to:

  • demonstrate knowledge of how biochemistry, genetics, and molecular biology are used to elucidate both the function of cells and their organization into tissues;
  • recognize that biology has a basis in chemistry, physics, and mathematics;
  • describe how scientific method is used to explain natural phenomena;
  • use effective oral and written language skills to communicate scientific data and ideas;
  • understand safe laboratory practices and perform basic molecular biology techniques;
  • generate hypotheses, evaluate data, and design experiments to investigate a scientific problem; and
  • present advanced knowledge in the specialized fields of molecular and cell biology.

Academic Advising for the Program

Students should take full advantage of academic advising and should keep in frequent contact with the advisers to stay informed about late announcements of courses, changes in scheduling, and opportunities for special study. Transfer students should also consult the Transfer Information and Policy Section. For additional advice and information:

MCD Advising
389 Thimann Labs
mcdadvising@ucsc.edu

Getting Started in the Major: Frosh

Prerequisites

Due to the demanding nature of the major, students must begin their science coursework as early as possible. MATH 11A or MATH 16A or MATH 19A; CHEM 3A, CHEM 3B, CHEM 3C, and CHEM 8A; and BIOL 20A, BIOE 20B, and BIOL 20L must be completed before the sixth quarter in order for students to qualify for admission to MCD biology-sponsored majors, including the biology B.S., human biology B.S., molecular, cell and developmental biology B.S., and neuroscience B.S. majors. For an overview of prerequisites and getting started in the major, please visit our MCD Biology B.S. website.

An online mathematics placement examination is required to enroll in a math course. Biological science majors are expected to take this examination and are encouraged to work in the learning modules until they place into calculus. For more information see the mathematics placement website.

Transfer Information and Policy

Transfer Admission Screening Policy

MCD Biology encourages applications from transfer students in the biological sciences. The department has a major qualification policy that limits access to the program to students who have successfully completed a subset of foundational coursework. Transfer students are held to similar criteria when being assessed for admission to UC Santa Cruz as an MCD-sponsored major. See qualifying for the major as a transfer applicant for more information.

To be considered for admission as a proposed molecular, cell and developmental biology B.S. major, transfer students must complete the following courses or their equivalents prior to transfer, by the end of the spring term for students planning to enter in the fall.

One of these options
Either these courses

CHEM 1AGeneral Chemistry

5

CHEM 1BGeneral Chemistry

5

CHEM 1CGeneral Chemistry

5

or these courses

CHEM 3AGeneral Chemistry

5

CHEM 3BGeneral Chemistry

3

CHEM 3CGeneral Chemistry

3

or these courses

CHEM 4AAdvanced General Chemistry: Molecular Structure and Reactivity

5

CHEM 4BAdvanced General Chemistry: Molecular Structure and Reactivity

5

Plus these courses
CHEM 8AOrganic Chemistry

5

BIOL 20ACell and Molecular Biology

5

BIOL 20LExperimental Biology Laboratory

2

BIOE 20BDevelopment and Physiology

5

Plus, one of the following calculus courses:
MATH 11ACalculus with Applications

5

MATH 16AMathematics for Life and Environmental Sciences

5

MATH 19ACalculus for Science, Engineering, and Mathematics

5

BIOL 20L is not required for students who have completed BIOL 20A and BIOE 20B at California community colleges.

In addition, the following courses are recommended prior to transfer to ensure timely graduation.
One of the following courses
MATH 11BCalculus with Applications

5

MATH 16BMathematics for Life and Environmental Sciences

5

MATH 19BCalculus for Science, Engineering, and Mathematics

5

Plus one of the following options
Either this course

STAT 5Statistics

5

or these courses

STAT 7Statistical Methods for the Biological, Environmental, and Health Sciences

5

STAT 7LStatistical Methods for the Biological, Environmental, and Health Sciences Laboratory

2

Plus both of the following courses
CHEM 8BOrganic Chemistry

5

CHEM 8LOrganic Chemistry Laboratory

2

Please see our preparing to transfer as an MCD major for more complete information.

Prospective students are encouraged to prioritize courses required and recommended for major preparation, and may additionally complete courses that articulate to UC Santa Cruz general education requirements as time allows.

Students who are proposed in a different major and have advanced standing when they enter UCSC require permission from the department to change into the major. Admission to the major is not guaranteed.

Getting Started in the Major: Transfer Students

Transfer students who have met the major qualification requirements are encouraged to declare the major during their first quarter at UC Santa Cruz. Transfer students should complete the required courses in genetics (BIOL 105), biochemistry (BIOL 100), and molecular biology (BIOL 101 and BIOL 101L) by the end of their first year at UCSC since they are prerequisites for the majority of other required courses.

Major Qualification Policy and Declaration Process

Major Qualification

The Department of Molecular, Cell and Developmental Biology has a qualification policy that applies to the biology B.S., molecular, cell and developmental biology B.S., and neuroscience B.S. majors.

To qualify for any of these majors, students must pass (with a grade of C or better) the following courses or their equivalents:

One of the following courses
MATH 11ACalculus with Applications

5

MATH 16AMathematics for Life and Environmental Sciences

5

MATH 19ACalculus for Science, Engineering, and Mathematics

5

Plus one of the following options
Either these courses

CHEM 3AGeneral Chemistry

5

CHEM 3BGeneral Chemistry

3

CHEM 3CGeneral Chemistry

3

or these courses

CHEM 4AAdvanced General Chemistry: Molecular Structure and Reactivity

5

CHEM 4BAdvanced General Chemistry: Molecular Structure and Reactivity

5

Note: This requirement may also be satisfied with prior completion of CHEM 1A, CHEM 1B, and CHEM 1C or equivalent.

Previous to July 1, 2023, the General Chemistry series, offered by the Department of Chemistry and Biochemistry, was listed in the General Catalog as Chemistry 1A, 1B and 1C, with associated laboratories Chemistry 1M and 1N. As of academic year 2023-24, this series was replaced with two distinct series: Chemistry 3A, 3B and 3C, with labs Chemistry 3BL and 3CL; or Chemistry 4A and 4B with labs Chemistry 4AL and BL. Descriptions of these two series are provided here.

Plus these courses
CHEM 8AOrganic Chemistry

5

BIOL 20ACell and Molecular Biology

5

BIOL 20LExperimental Biology Laboratory

2

BIOE 20BDevelopment and Physiology

5

All qualification courses must be completed prior to the major declaration deadline. Students with two or more grades of NP, C-, D+, D, D-, or F in the policy courses are not qualified to declare.

When assessing qualification:

  • All courses must be taken for a letter grade, see Letter Grade Policy below.
  • Students with AP credit for MATH 11A or MATH 19A, BIOL 20A, BIOE 20B, and/or CHEM 3A, need only pass the remaining qualification policy courses.
  • Every student who satisfies the major qualification requirements and who petitions to declare the major by the campus major declaration deadline (i.e., before enrolling in their third year or the equivalent) will be admitted to the major. Students who satisfy the major admission requirements, but who petition to declare the major after the campus major declaration deadline will be considered on a case-by-case basis for admission to the major; admission is not guaranteed.

Appeal Process

Students who are not eligible to declare the major may submit an appeal to the Molecular, Cell and Developmental Biology faculty adviser. The department will notify the student and their college of the outcome of the appeal within 15 working days of the quarterly appeal deadline. See our appeal process for more information.

How to Declare a Major

Petition to declare your major as soon as you have met qualification requirements and/or reach your declaration deadline quarter, whichever comes first.

A student's petition to declare the major will either be approved, denied, or provided with conditions (e.g., completion of some courses with certain grades) that will be resolved within at most one more enrolled quarter, even if they have not completed major qualification courses.

The Petition for Major/Minor declaration form can be accessed by going to MyUCSC and navigating to the Student Homepage and selecting the Undergraduate Student eForms tile > Petition for Major/Minor.

Letter Grade Policy

All courses that are taken to satisfy any major requirement must be taken for a letter grade.

Course Substitution Policy

At least half of the upper-division courses required for the major must be taken at UC Santa Cruz, not as transfer credits from another institution. If a student plans to transfer to UCSC from another institution, the student is advised to contact MCD Advising at UCSC before enrolling in upper-division courses at the student’s institution or any institution other than UCSC. This advising will help students understand the limitation of transferring upper-division courses from other institutions to UCSC. For more information on transferring courses to UCSC, please consult the undergraduate website.

Once matriculated, a student must receive permission from the department to satisfy the BIOL 20A, BIOL 100, BIOL 105, BIOL 101 or BIOL 110 requirements with courses taken at other institutions. Students who wish to receive credit toward the major for these or other courses taken either at UCSC or at another institution should contact MCD Advising.

Double Majors and Major/Minor Combinations Policy

Students interested in pursuing multiple majors within the biological sciences may NOT declare the following combination of majors:

  • Biology (B.A., B.S., or minor) and any other biological sciences major
  • Any combination of the following: human biology; molecular, cell and developmental biology; neuroscience; or biochemistry and molecular biology

Should a student choose to double major, they must qualify for and complete the disciplinary communication and comprehensive requirements for each of the majors.

Study Abroad

The UC Education Abroad Program (EAP) offers qualified students unique opportunities to broaden their educational horizons. The MCD Biology Department encourages interested students to participate. Many programs are in English-speaking countries or use English for advanced courses. Many programs offer small classes, extensive laboratories, and/or field research experience.

Students interested in study abroad need to get an early start on their basic science requirements, including chemistry, mathematics, and introductory biology and must declare their major prior to applying to go abroad. Students interested in studying abroad should visit the EAP office as soon as possible to begin planning. They should also seek advice about their EAP plan for major courses at UC Santa Cruz from MCD Advising and receive their approval.

Honors

Honors in the majors are awarded to graduating students whose academic performance demonstrates excellence at a grade point average (GPA) of 3.5 or above. Highest honors are awarded to those students whose performance demonstrates the highest level of excellence and results in a GPA of 3.8 or above.

Medical and Professional School Admission

Medical and professional school admissions requirements vary; students should verify that their coursework will satisfy the admissions requirements of the programs to which they plan to apply.

Requirements and Planners

Course Requirements

Lower-Division Courses

All of the following courses:
BIOL 20ACell and Molecular Biology

5

BIOL 20LExperimental Biology Laboratory

2

BIOE 20BDevelopment and Physiology

5

BIOE 20CEcology and Evolution

5

CHEM 8AOrganic Chemistry

5

CHEM 8BOrganic Chemistry

5

CHEM 8LOrganic Chemistry Laboratory

2

Plus one of the following options:
Either these courses

CHEM 3AGeneral Chemistry

5

CHEM 3BGeneral Chemistry

3

CHEM 3BLGeneral Chemistry Lab

2

CHEM 3CGeneral Chemistry

3

CHEM 3CLGeneral Chemistry Lab

2

or these courses

CHEM 4AAdvanced General Chemistry: Molecular Structure and Reactivity

5

CHEM 4ALAdvanced General Chemistry Lab

2

CHEM 4BAdvanced General Chemistry: Molecular Structure and Reactivity

5

CHEM 4BLAdvanced General Chemistry Lab

2

Note: This requirement may also be satisfied with prior completion of CHEM 1A, CHEM 1B, CHEM 1C, and CHEM 1N, or equivalent.

Previous to July 1, 2023, the General Chemistry series, offered by the Department of Chemistry and Biochemistry, was listed in the General Catalog as Chemistry 1A, 1B and 1C, with associated laboratories Chemistry 1M and 1N. As of academic year 2023-24, this series was replaced with two distinct series: Chemistry 3A, 3B and 3C, with labs Chemistry 3BL and 3CL; or Chemistry 4A and 4B with labs Chemistry 4AL and BL. Descriptions of these two series are provided here.

Plus one of the following options:
Either these courses

MATH 11ACalculus with Applications

5

MATH 11BCalculus with Applications

5

or these courses

MATH 16AMathematics for Life and Environmental Sciences

5

MATH 16BMathematics for Life and Environmental Sciences

5

or these courses

MATH 19ACalculus for Science, Engineering, and Mathematics

5

MATH 19BCalculus for Science, Engineering, and Mathematics

5

Students may transition between the MATH 11 and MATH 19 series per the Calculus Series Transition Policy.

Plus one of the following options
Either this course

STAT 5Statistics

5

or these courses

STAT 7Statistical Methods for the Biological, Environmental, and Health Sciences

5

STAT 7LStatistical Methods for the Biological, Environmental, and Health Sciences Laboratory

2

Plus all of the following courses:
PHYS 6AIntroductory Physics I

5

PHYS 6LIntroductory Physics I Laboratory

1

PHYS 6BIntroductory Physics II

5

PHYS 6CIntroductory Physics III

5

Upper-Division Courses

All of the following courses:
BIOL 100Biochemistry

5

BIOL 101Molecular Biology

5

BIOL 105Genetics

5

BIOL 110Cell Biology

5

BIOL 120Developmental Biology

5

BIOL 104LCoronavirus Bioinformatics Lab

2

Plus one of the following courses:
BIOL 101LMolecular Biology Laboratory

2

BIOL 102LToxic RNA Lab II

5

BIOL 107LSynthetic Gene Regulation Lab II

5

BIOL 122KPhage Biology Lab I

5

CHEM 160KBiochemistry Research Laboratory

5

CHEM 161KChemical Biology Research Laboratory

5

Electives

At least two elective courses from the following list, one of which must be a BIOL course.

Note: Lecture/lab combinations count as one course.

BIOL 111AImmunology I

5

BIOL 112Principles of Virology

5

BIOL 114Cancer Cell Biology

5

BIOL 115Eukaryotic Molecular Biology

5

BIOL 117Global Health and Neglected Diseases

5

BIOL 118Principles of Human Genetics

5

BIOL 124Optical Imaging for Biological Research

3

BIOL 125Introduction to Neuroscience

5

BIOL 127Mechanisms of Neurodegenerative Disease

5

BIOL 130Human Physiology

5

BIOE 109Evolution

5

BIOE 135Plant Physiology

5

BIOE 135LPlant Physiology Laboratory

2

BME 110Computational Biology Tools

5

BME 130Genomes

5

BME 160Research Programming in the Life Sciences

6

BME 178Stem Cell Biology

5

METX 100Introduction to Microbiology

5

METX 133Medical Microbiology

5

METX 140Molecular Biology and Microbial Genetics

5

METX 150Applied and Environmental Microbiology

5

PHYS 180Biophysics

5

One of the following laboratory courses:
BIOL 100LBiochemistry Laboratory

5

BIOL 103LToxic RNA Lab III

5

BIOL 105LEukaryotic Genetics Laboratory

5

BIOL 106LEukaryotic Genetic Engineering

5

BIOL 108LSynthetic Gene Regulation Lab III

5

BIOL 109LYeast Molecular Genetics Laboratory

5

BIOL 115LEukaryotic Molecular Biology Laboratory

5

BIOL 120LDevelopment Laboratory

5

BIOL 121LEnvironmental Phage Biology Laboratory

5

BIOL 122LPhage Biology Lab II

5

BIOL 186LUndergraduate Research in MCD Biology

5

CHEM 160LBiochemistry Research Laboratory

5

CHEM 161LChemical Biology Research Laboratory

5

This course will satisfy the disciplinary communication (DC) and comprehensive requirement.

Disciplinary Communication (DC) Requirement

Students of every major must satisfy that major's upper-division disciplinary communication (DC) requirement. The DC requirement in molecular, cell, and developmental biology is satisfied by completing one of the following courses:

BIOL 100LBiochemistry Laboratory

5

BIOL 103LToxic RNA Lab III

5

BIOL 105LEukaryotic Genetics Laboratory

5

BIOL 106LEukaryotic Genetic Engineering

5

BIOL 108LSynthetic Gene Regulation Lab III

5

BIOL 109LYeast Molecular Genetics Laboratory

5

BIOL 115LEukaryotic Molecular Biology Laboratory

5

BIOL 120LDevelopment Laboratory

5

BIOL 121LEnvironmental Phage Biology Laboratory

5

BIOL 122LPhage Biology Lab II

5

BIOL 186LUndergraduate Research in MCD Biology

5

CHEM 160LBiochemistry Research Laboratory

5

CHEM 161LChemical Biology Research Laboratory

5

Comprehensive Requirement

All majors have a comprehensive requirement. For the MCD Biology B.S., this requirement can be satisfied by receiving a passing grade in an independent research laboratory:

Choose one of the following courses:

BIOL 100LBiochemistry Laboratory

5

BIOL 103LToxic RNA Lab III

5

BIOL 105LEukaryotic Genetics Laboratory

5

BIOL 106LEukaryotic Genetic Engineering

5

BIOL 108LSynthetic Gene Regulation Lab III

5

BIOL 109LYeast Molecular Genetics Laboratory

5

BIOL 115LEukaryotic Molecular Biology Laboratory

5

BIOL 120LDevelopment Laboratory

5

BIOL 121LEnvironmental Phage Biology Laboratory

5

BIOL 122LPhage Biology Lab II

5

BIOL 186LUndergraduate Research in MCD Biology

5

CHEM 160LBiochemistry Research Laboratory

5

CHEM 161LChemical Biology Research Laboratory

5

Planners

The tables below are for informational purposes and do not reflect all university, general education, and credit requirements. See Undergraduate Graduation Requirements for more information.

Sample First-Year Four-Year Planner

Additional first-year sample planners

Fall Winter Spring Summer
Entering
1st (frosh) CHEM 3A CHEM 3B & CHEM 3BL CHEM 3C & CHEM 3CL
MATH 11A or 19A MATH 11B or 19B BIOL 20A
2nd (soph) BIOE 20B PHYS 6A & PHYS 6L BIOL 100
BIOL 20L CHEM 8B PHYS 6B
CHEM 8A & CHEM 8L
3rd (jr) BIOL 101 & BIOL 101L BIOL 105 BIOL 110
PHYS 6C BIOE 20C STATS 5 or
STAT 7/STAT 7L
4th (sr) MCD Elective #1 BIOL 120 MCD Elective #2
BIOL 104L UD LAB/DC

* WRIT 2 should be taken in or before spring quarter of the second year.

The following general education requirements will be fulfilled by the major requirements listed in the above planner: MF, SI, and SR. In addition to the general education requirements satisfied by the above courses, a student will also need to complete courses satisfying the CC, ER, IM, TA, PE, and PR general education requirements.

Sample Transfer Two-Year Planner

Additional transfer student sample planners

Fall Winter Spring Summer
Entering
3rd (jr) BIOL 105 BIOL 100 BIOL 101 & BIOL 101L
STAT 5 or
STAT 7/STAT 7L
PHYS 6A & PHYS 6L PHYS 6B
4th (sr) BIOL 110 UD LAB/DC MCD Elective #1
PHYS 6C BIOL 120 MCD Elective #2

This planner assumes that a student has completed all UC Transfer Pathway courses:

  • General biology with lab (full introductory sequence) BIOL 20A, BIOE 20B, BIOL 20L, BIOE 20C
  • General chemistry with lab (one-year sequence) CHEM 3A, CHEM 3B & CHEM 3BL and CHEM 3C & CHEM 3CL
  • Calculus for STEM majors (one-year sequence) MATH 11A and MATH 11B
  • Organic chemistry (full sequence with lab) CHEM 8A & CHEM 8L and CHEM 8B