Information and Policies
Introduction
Research at the macromolecular, molecular, and atomic levels is revolutionizing our understanding of the fundamental processes of life. Students interested in joining this search are best prepared by undertaking coursework in biology, chemistry, physics, mathematics, and computer science. The undergraduate major in Biochemistry and Molecular Biology (BMB) is offered by faculty who are actively engaged in research on biological systems.
Students who declare the BMB major earn a bachelor of science (B.S.) degree. The BMB major constitutes an integrated curriculum of basic instruction in biology, chemistry, mathematics, and physics, followed by the opportunity to pursue advanced study in specialized areas of interest. In modern, well-equipped laboratories, distinguished faculty are engaged in frontline research at UCSC. The Department of Chemistry and Biochemistry and the Department of Molecular, Cell, and Developmental Biology each host a very active seminar series in which internationally-recognized scientists present their current research findings. Advanced BMB undergraduates are encouraged to attend.
The BMB program features close faculty-student interaction, stimulating learning environments, and opportunities for independent research and study. Students majoring in BMB are encouraged to become involved in research under the guidance of a faculty sponsor. Many students participating in this aspect of the program have made important contributions to the scientific literature.
Given the wide scope and interdisciplinary nature of this program, a considerable degree of flexibility has been incorporated into the major. All prospective majors should see the BMB academic advisor in the Chemistry and Biochemistry Department Office as early as possible. Junior transfer students or others with questions should consult the program website. A double major of BMB with the biological sciences majors or chemistry is not permitted. No minor is offered.
Academic Advising for the Program
The Chemistry and Biochemistry advisor provides counsel to undergraduate majors. Students are encouraged to seek out advising and assistance in planning their academic careers to ensure completion of their major in a timely manner. For assistance, please contact Chemistry Advising at chemistryadvising@ucsc.edu or visit our department website. Transfer students should also consult the Transfer Information and Policy Section below.
Getting Started in the Major
Prospective majors should have a solid foundation in high school mathematics; familiarity with algebra, logarithms, trigonometry, and analytic geometry is particularly required. Students taking chemistry at UC Santa Cruz begin with CHEM 1A or CHEM 1B, both of which require a strong background in high school chemistry.
Prerequisites
In order to determine what preparation may be needed to succeed in the general chemistry sequence, CHEM 1A, CHEM 1B, and CHEM 1C students are encouraged to take the Chemistry Self-Assessment Examination.
Program Learning Outcomes
Learning outcomes summarize the most important knowledge, skills, abilities, and attitudes that students are expected to develop over the course of their studies. The program learning outcomes clearly communicate the faculty’s expectations to students, provide a framework for faculty evaluation of the curriculum based on empirical data, and help improve and measure the impact of implemented changes.
Students graduating with a B.S. in biochemistry and molecular biology should be able to:
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demonstrate mastery of a broad set of chemical and biological knowledge concerning the fundamentals in the basic areas of the discipline (organic, inorganic, analytical, physical, biochemistry, and molecular biology);
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solve area-specific problems by identifying the essential parts of a problem, formulating a strategy for solving the problem, applying appropriate techniques to arrive at a solution, testing the correctness of the solution, and interpreting their results;
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use modern library search tools (such as SciFinder, PubMed, or Web of Science) to locate and retrieve scientific information about topics relating to chemistry and biology;
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know and follow the proper procedures and regulations for safe handling and use of chemicals, nucleic acids and common laboratory instruments;
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understand the objective of their chemical and biological experiments, properly carry out the experiments, and appropriately record and analyze the results;
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use computers in data acquisition and processing, and use available software as a tool in data analysis;
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use standard laboratory equipment, modern instrumentation, and classical techniques to carry out experiments;
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communicate the concepts and results of their laboratory experiments through effective writing and/or oral communication using the discipline standards for reporting and citation; and
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collaborate effectively as part of a team to solve problems, debate different points of view, and interact productively with a diverse group of team members.
Major Qualification Policy and Declaration Process
Major Qualification
Students must complete the following qualification courses, or their equivalents, each with a grade of C (2.0) or better and with a cumulative grade point average (GPA) of 2.50 or greater in these five required courses:
Note that since CHEM 1A is a prerequisite for CHEM 1C, students must also complete CHEM 1A with a grade of C or better. Transfer students must have a full year of general chemistry.
Students must have taken CHEM 8B or be enrolled prior to the end of year two.
Plus one of the following options:
When calculating GPA to determine qualification:
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All courses must be taken for a letter grade, see the Letter Grade Policy section below.
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For courses required to qualify for the major that have been satisfied with Advanced Placement credit based on an AP examination score (See Admissions AP Chart), students may substitute a grade of A for each course when calculating their GPA.
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Students with two or more grades of NP, C-, D+, D, D-, or F in courses required to qualify for the major are not eligible to declare.
Transfer students should also consult the Transfer Information and Policy Section.
Appeal Process
Students may appeal to the major either prior to OR after submitting a petition to declare and being denied (in the latter case, appeals must be submitted within 15 days from the date the denial notification was sent).
To appeal to declare a Chemistry major, submit a letter to the chemistry advisor, chemistryadvising@ucsc.edu.
Within 15 days of receipt of the appeal, the department will notify the student and their affiliated college of the decision. For more information about the appeal process, see the Appeal Process on the Chemistry website.
How to Declare a Major
You may declare a major as early as you would like if you have decided which major to pursue and have satisfied prerequisites or qualification requirements (if any) for the major. Students should submit a petition to declare as soon as they complete the major qualification requirements or reach their declaration deadline quarter (whichever comes first).
Students who enter UC Santa Cruz as frosh are required to formally petition to declare a major by the campus deadline in their sixth quarter and before enrolling in their third year (or equivalent). Upper-division transfer students are required to be declared in a major by the deadline in their second term at UCSC.
Each major/minor advising office has a process for declaring. To initiate the process to declare, please complete the online declaration petition located on the Department of Chemistry website. For assistance, please contact chemistry advising at chemistryadvising@ucsc.edu.
Students petitioning when the campus declaration deadline is imminent (i.e., in their sixth quarter, for students admitted as frosh), will either be approved, denied, or provided with conditions (e.g., completion of some courses with certain grades) that will be resolved within at most one more enrolled quarter, even if they have not completed major qualification courses.
Transfer Information and Policy
Transfer Admission Screening Policy
The following courses or their equivalents are required prior to transfer, by the end of the spring term for students planning to enter in the fall.
Plus one of the following options:
Students must complete the above courses or their equivalents, with a grade of C or better, and have a cumulative GPA in these courses of 2.5 or greater.
Students must have passed CHEM 8B or be currently enrolled in it prior to transfer matriculation. This requirement will be applied to students entering UCSC in the fall of 2022 and thereafter.
Prospective students are encouraged to prioritize required and recommended major preparation, and may additionally complete courses that articulate to UC Santa Cruz general education requirements as time allows.
For more information on qualifying for the major as a transfer applicant, see the Transfer Students webpage.
Students Entering at the Junior Level
Students entering at the junior level who wish to graduate in two years after coming to UC Santa Cruz should also complete the equivalents of the following preparatory courses prior to transfer:
As well as one of the following:
While not a required course, MATH 22 is recommended for students who wish to take CHEM 163A/CHEM 163B instead of BIOC 163A/BIOC 163B
The biochemistry major also requires one year of calculus-based physics with lab and one term of statistics before graduation from UCSC. Students can complete these courses at community college if their schedule allows, but the courses can also be completed after transfer without negatively affecting competitiveness for admission to UCSC.
Students who complete only the minimal introductory coursework prior to transfer are more likely to take longer to complete their degree. More information on transfer pathways for chemistry at the University of California may be found on the Admissions website.
Students planning to transfer to UCSC as a biochemistry and molecular biology major from a California community college should reference assist.org to determine which courses are equivalent to these required courses.
Getting Started at UCSC as a Transfer Student
Transfer students are highly encouraged to meet with the chemistry academic advisor in their first quarter. For assistance with advising, please contact Chemistry Advising at chemistryadvising@ucsc.edu. More information specific to transfer students may also be found on our department website.
Students who have satisfied the screening requirements can declare their major any time after coming to UC Santa Cruz but are required to be declared in a major by the applicable deadline; in their second term at UCSC for students entering at the junior level.
Transfer students who are proposed in a different major (other than chemistry) and have advanced standing when they come to UC Santa Cruz require permission from the department to change into the major. Admission to the major is not guaranteed. For more information on qualifying for the major as a transfer applicant, see the Transfer Students webpage.
Letter Grade Policy
For all students entering UCSC in fall 2001 and later, all courses used to satisfy any of the major requirements must be taken for a letter grade.
Additionally, letter grades of C or higher must be attained in all major courses to meet requirements for graduation.
Course Substitution Policy
At least half of the upper-division courses (numbered 100–199) required for any biochemistry and molecular biology major must be taken through the chemistry or biology programs at UCSC, not as transfer credits from another department or institution. Students are advised to contact the Chemistry and Biochemistry Department undergraduate advisor before enrolling in numerous upper-division courses at other institutions. For more information on transferring courses to UCSC, please consult the Chemistry and Biochemistry Department website.
Double Majors and Major/Minor Combinations Policy
A double major of BMB with the biological sciences majors or chemistry is not permitted. No minor is offered.
Honors
Honors in the majors are awarded to graduating students whose academic performance demonstrates excellence at a GPA of 3.5 or above. Highest honors are awarded to those students whose performance demonstrates the highest level of excellence and results in a GPA of 3.8 or above.
Program Planning Notes
Students who do not begin the lower-division requirements during their first year, and who do not complete the organic chemistry requirements by the end of their second year, will have difficulty completing the program within four years. The BMB academic advisor works closely with students interested in pursuing the major to ensure that they begin the program immediately and follow the appropriate steps toward completion.
It is strongly recommended that students avail themselves of the opportunities to obtain firsthand research experience through either independent study, senior thesis research, or by working in a faculty research lab.
A number of graduate courses in Biochemistry and Molecular Biology are offered by both the molecular, cell, and developmental biology (MCDB), and chemistry and biochemistry departments. Advanced undergraduates possessing the necessary prerequisites may take one or more of these courses with the consent of the instructor.
Materials Fee
Biochemistry and Molecular Biology students should be aware of the materials fee required for some laboratory courses. The fee is billed to the student’s account for specific laboratory materials purchased through the university. Fees generally range from $18 to $75 per course. Students may incur additional expenses purchasing individual supplies.
Requirements and Planners
Course Requirements
Lower-Division Courses
General Chemistry
Calculus
Statistics
Intro Biology
Organic Chemistry
Physics
A student may combine the PHYS 5 series with the PHYS 6 series to complete this portion of the major requirement(s). For example, a student can take and complete PHYS 5A and PHYS 5L and then take and complete PHYS 6B and PHYS 6M and PHYS 6C and PHYS 6N.
Upper-Division Courses
Biochemistry and Molecular Biology
Genetics
Cell Biology
Eukaryotic Molecular Biology
Physical Chemistry
| BIOC 163A | Quantum Mechanics, Spectroscopy and Molecular Structure for Biochemistry and Molecular Biology | 5 |
| BIOC 163B | Biochemical Thermodynamics and Statistical Mechanics for Biochemistry and Molecular Biology | 5 |
A student may combine the CHEM 163 series with the BIOC 163 series to complete this portion of the major requirement(s). For example, a student can take and complete CHEM 163A and then take and complete BIOC 163B. Be aware of the MATH 22 prerequisite for CHEM 163A and CHEM 163B.
Senior Exit Lab
One of the following laboratory courses (also satisfies the Disciplinary Communication (DC) and Comprehensive Requirement):
Disciplinary Communication (DC) Requirement
Students of every major must satisfy that major’s upper-division Disciplinary Communication (DC) requirement. The DC requirement in Biochemistry and Molecular Biology is satisfied by completing one of the Senior Exit Labs listed in the previous section.
The DC requirement must be satisfied at UC Santa Cruz and may not be transferred from another institution.
Comprehensive Requirement
Students must satisfy the comprehensive requirement by receiving a passing letter grade in any of the Senior Exit Labs listed in the previous section. In addition, students are encouraged to get research experience by working in a faculty research lab.
Planners
This is the ideal academic plan for those pursuing the biochemistry and molecular biology B.S. major. Please see an academic advisor in the Chemistry Department to create your specific official academic plan.
Sample Four-Year Planner
| |
Fall |
Winter |
Spring |
| 1st (frosh) |
MATH 11A
or MATH 19A |
MATH 11B
or MATH 19B
|
BIOL 20A |
| CHEM 1A |
CHEM 1B & CHEM 1M |
CHEM 1C & CHEM 1N |
| |
|
|
| 2nd (soph) |
BIOE 20B |
MATH 22 (optional) |
BIOL 105 |
| CHEM 8A & CHEM 8L |
CHEM 8B & CHEM 8M |
STAT 5
or STAT 7 & STAT 7L |
| |
BIOL 20L |
|
| 3rd (junior) |
BIOC 100A |
BIOC 100B |
BIOC 100C |
| BIOL 101L |
PHYS 6A & PHYS 6L |
PHYS 6B & PHYS 6M |
| |
|
|
| 4th (senior) |
BIOC 163A
or *CHEM 163A |
BIOC 163B
or CHEM 163B |
Senior exit lab |
| PHYS 6C & PHYS 6N |
BIOL 115 |
BIOL 110 |
Courses are subject to being offered in different terms. Please check departmental websites for updates on course offerings.
Three of the required general education requirements will be fulfilled by the major requirements listed in the above planner (MF, SI & SR). In addition to the specific courses shown in these planners, a student will also need to complete courses satisfying the following general education requirements: Cross-Cultural Analysis, Ethnicity & Race, Interpreting Arts & Media, Textual Analysis & Interpretation, Perspectives, and Practice.
Sample Transfer Two-Year Planner
This is the ideal planner for students who have transferred in with both the required and highly recommended UC Transfer Pathway courses. Note: Failure to complete both the required and highly recommended courses prior to transfer may require additional time to degree. Please refer to the following academic planners that detail student plans with only the minimum transfer requirements completed. Please see an academic advisor in the Chemistry Department to create your specific official academic plan.
Sample Transfer Two-Year Planner
| |
Fall |
Winter |
Spring |
| 1st (junior) |
BIOC 100A |
BIOC 100B |
BIOC 100C |
| BIOL 101L |
PHYS 6A & PHYS 6L |
PHYS 6B & PHYS 6M |
|
STAT 5
or STAT 7 & STAT 7L |
|
BIOL 105 |
| 2nd (senior) |
BIOC 163A
or *CHEM 163A |
BIOC 163B
or CHEM 163B |
Senior exit lab |
| PHYS 6C & PHYS 6N |
BIOL 115 |
BIOL 110 |
| |
|
|
UC Transfer Pathway courses:
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General biology with lab (full introductory sequence) BIOL 20A, BIOE 20B, BIOL 20L
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General chemistry with lab (one-year sequence) CHEM 1A, CHEM 1B & CHEM 1M, CHEM 1C & CHEM 1N
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Calculus for STEM majors (one-year sequence) MATH 11A & MATH 11B, MATH 22
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Organic chemistry with lab (one-year sequence) CHEM 8A & CHEM 8L, CHEM 8B & CHEM 8M
Courses are subject to being offered in different terms. Please check departmental websites for updates on course offerings.